Age-standard attributes out-of 86,149 women in this new NHS We inside the 1994 and 94,715 feamales in the fresh new NHS II inside the 1995 because of the quintiles away from magnesium, potassium, and you will calcium supplements consumption step 1
Model 2 is modified for model step 1 and also for consumption out of potassium and you may calcium supplements (quintiles out-of g/d)
Regarding multivariate analyses, total and you can dietary magnesium intakes was in fact inversely associated with the chance of total however, ischemic otherwise hemorrhagic coronary arrest ( Dining table dos). The fresh pooled multivariate RR to own complete stroke is actually 0.87 (95% CI: 0.78, 0.97; P-trend = 0.07) toward research of women regarding high which have reduced quintiles away from total magnesium consumption; while the new pooled multivariate RR towards the research off high that have lowest quintiles away from fat loss magnesium consumption try 0.81 (95% CI: 0.69, 0.94; P-pattern = 0.001) having total coronary attack. Full potassium consumption try inversely in the danger of total but perhaps not ischemic or hemorrhagic stroke ( Dining table 3). Getting analysis of females about large with reasonable quintiles of complete potassium consumption, this new pooled multivariate RR to have full stroke is 0.89 (95% CI: 0.80, 0.99; P-trend = 0.01). Multivariate RRs for magnesium and you can potassium was basically attenuated whenever the step 3 minerals had been within the designs concurrently (multivariate model dos). There is certainly zero high organization between full or dieting calcium supplements consumption and complete, ischemic, otherwise hemorrhagic coronary arrest ( Table cuatro). Multivariate RRs for overall magnesium (Extra Table step one), total potassium (Supplemental Dining table dos), overall calcium supplements (Supplemental Dining table step 3), losing weight magnesium (Supplemental Desk 4), fat reduction potassium (Extra Desk 5), and you may weight loss calcium supplements (Extra Dining table six) and you will chance of full, ischemic, and you may hemorrhagic strokes per cohort by themselves are shown throughout the supplemental thing.
Pooled RRs (95% CIs) out-of total, ischemic, and you will hemorrhagic strokes because of the quintiles out of complete and losing weight magnesium consumption for the 86,149 ladies in the fresh new NHS We and you will 94,715 women in the latest NHS II step one
Values are the n of cases. Cox proportional hazards models were free Hispanic Sites sex dating used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.
Pooled RRs (95% CIs) away from total, ischemic, and you can hemorrhagic shots by quintiles out-of total and you will weightloss magnesium intake from inside the 86,149 women in this new NHS We and you can 94,715 women in the new NHS II step one
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.